Episode 60

Obesity is not about Forks and Willpower

Published on: 13th December, 2024

Obesity: Not Just About Forks and Willpower

For years, obesity has been misunderstood, oversimplified, and even stigmatized. It's been framed as a personal failing, a lifestyle choice, or simply a matter of "eating less and moving more." But science tells a different, more nuanced story—one where our brains, biology, and ultra-processed food environment play starring roles. And thanks to groundbreaking medications like GLP-1 drugs, we’re gaining a clearer picture of how obesity works and how to treat it.

Let’s dive into why obesity is a disease, how ultra-processed foods exacerbate it, and why we need to ditch the harmful myth that obesity is a lifestyle choice.

The Myth of "Just Eat Less and Move More"

"Just eat less and move more." It’s the phrase everyone loves to repeat—and no one finds helpful. This simplistic advice ignores the reality that obesity is not merely about calories in and calories out. It’s about a complex interplay between your biology, brain chemistry, and environment.

Obesity isn’t a character flaw or a lack of willpower. If it were, we wouldn’t see an obesity epidemic in societies flooded with cheap, ultra-processed foods engineered to make us eat more. These foods hijack our biology, overpowering the mechanisms our bodies use to regulate hunger and fullness.

The Hungry Brain: Why You Can’t Stop Eating

Our brains evolved to keep us alive in times of scarcity. Back in the caveman days, this was helpful. Today, it’s less so because our brains are still wired to seek out high-calorie foods to avoid starvation—even when we’re surrounded by abundance.

When you eat ultra-processed foods, they light up the reward centers in your brain like a Christmas tree. These foods—laden with sugar, fat, and salt—trigger the release of dopamine, the same neurotransmitter involved in addiction. It’s no wonder we keep going back for more.

Adding to the complexity, hormones like ghrelin (the "hunger hormone") and leptin (the "fullness hormone") can go haywire in people with obesity. Ultra-processed foods amplify ghrelin’s effects, making you feel hungrier while reducing your sensitivity to leptin, so you never feel full. It’s a biological double whammy.

Citation: Studies show that diets high in ultra-processed foods increase calorie consumption by about 500 calories per day compared to diets of unprocessed foods (Hall et al., 2019).

GLP-1: The Game-Changing Hormone

Here’s where things get interesting: GLP-1, or glucagon-like peptide-1, is a hormone that helps regulate appetite. It tells your brain, “You’re full; you can stop eating now.” But for many people with obesity, this system doesn’t work properly. Their brains don’t get the message, leading to overeating.

Enter GLP-1 receptor agonists like semaglutide and liraglutide—medications that mimic the effects of GLP-1. These drugs help regulate appetite, making people feel full sooner and reducing cravings. The results have been extraordinary: clinical trials show average weight loss of 15% or more with these medications, far outpacing what’s possible with lifestyle changes alone.

These drugs have done more than help people lose weight—they’ve also shifted the way we think about obesity. They show that obesity is a medical condition influenced by hormones and brain chemistry, not just a matter of willpower.

Citation: Clinical trials on GLP-1 receptor agonists show significant and sustained weight loss, with participants losing 15% or more of their body weight (Wilding et al., 2021).

Why Obesity Is a Disease, Not a Lifestyle Choice

The idea that obesity is a "lifestyle choice" is not only incorrect—it’s harmful. Framing obesity this way ignores the biological, genetic, and environmental factors that contribute to it. Worse, it stigmatizes people with obesity, making them feel like they’re to blame for their condition.

Obesity meets all the criteria for a chronic disease: it has a defined pathology (dysregulation of appetite and metabolism), it leads to complications (diabetes, heart disease, etc.), and it requires long-term management. Lifestyle factors like diet and exercise can influence obesity, but they’re not the sole cause. Blaming someone for their obesity is like blaming someone with asthma for living in a polluted city.

Citation: The American Medical Association classified obesity as a chronic disease in 2013, recognizing it as a condition requiring medical treatment (AMA, 2013).

Ultra-Processed Foods: The Real Culprit

If obesity is a fire, ultra-processed foods are the gasoline. These foods are engineered for maximum palatability, combining sugar, fat, and salt in ways that overwhelm our natural appetite-regulation systems. They’re calorie-dense, nutrient-poor, and often stripped of fiber, which would otherwise help us feel full.

Even worse, ultra-processed foods alter the way our brains respond to food. They increase cravings, reduce satiety, and encourage overeating. Over time, this can lead to weight gain and metabolic issues, creating a vicious cycle that’s hard to break.

Citation: Research shows that people who consume diets high in ultra-processed foods are more likely to develop obesity and metabolic diseases (Monteiro et al., 2018).

How GLP-1 Drugs Have Changed the Game

GLP-1 drugs have given us new tools to treat obesity—and new insights into its underlying causes. They’ve proven that obesity isn’t just about behavior; it’s about biology. When you treat obesity like a disease rather than a moral failing, people get better.

But these medications are just one piece of the puzzle. To tackle obesity on a larger scale, we need to address the broader food environment. That means making healthy, unprocessed foods more accessible, reducing the marketing of ultra-processed foods, and investing in public health initiatives that promote nutrition education.

Why Fat Shaming Is Harmful (and Wrong)

Let’s address the elephant in the room: fat shaming. The idea that you can "shame" someone into losing weight is not only cruel—it’s ineffective. Research shows that weight stigma leads to stress, low self-esteem, and even more weight gain. It’s a lose-lose situation.

Instead of shaming people for their weight, we need to focus on creating supportive environments that help everyone make healthier choices. That includes treating obesity as the complex, multifactorial disease that it is—not a personal failure.

Citation: Weight stigma is associated with increased psychological distress, unhealthy eating behaviors, and reduced motivation for physical activity (Puhl & Heuer, 2010).

Moving Forward: What We Can Do

Here’s how we can start to shift the conversation around obesity:

Acknowledge Obesity as a Disease: Let’s treat obesity like any other chronic condition with empathy and evidence-based care.

Focus on the Food Environment: We need to address the root causes of obesity, including the overabundance of ultra-processed foods.

Reduce Stigma: Stop blaming individuals for their weight. Instead, offer support and solutions.

Expand Access to GLP-1 Drugs: These medications are game-changers, but they’re expensive and not always covered by insurance. Making them accessible is crucial.

Conclusion: It’s Time to Change the Narrative

Obesity is not a lifestyle choice. It’s a complex, chronic disease driven by biology, brain chemistry, and the environment we live in. Thanks to advances in science, like GLP-1 drugs, we’re starting to understand and treat obesity in ways that are effective and compassionate.

The next time someone tells you to “just eat less and move more,” remind them that obesity is about much more than that. It’s time to move past the myths, embrace the science, and support people on their journey to better health.

And maybe, just maybe, it’s time to rethink that bag of chips.

References

Hall, K. D., et al. (2019). "Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain." Cell Metabolism.

Wilding, J. P. H., et al. (2021). "Once-Weekly Semaglutide in Adults with Overweight or Obesity." The New England Journal of Medicine.

Monteiro, C. A., et al. (2018). "Ultra-Processed Foods, Diet Quality, and Health Using the NOVA Classification System." Public Health Nutrition.

Puhl, R., & Heuer, C. (2010). "Obesity Stigma: Important Considerations for Public Health." American Journal of Public Health.

AMA (2013). "American Medical Association House of Delegates Resolution 420 (A-13)."

Transcript
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>> Dr. Terry Simpson: Here's a question for you. Is obesity a

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lifestyle choice? Short answer,

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Absolutely not. Long answer. That's

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what this podcast is about.

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Buckle up, because today we're going to unravel the

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complex, fascinating, and occasionally

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ridiculous way our brains, ultra

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processed food, and a little hormone called

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GLP1 are running the show when it comes to

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obesity. Oh, and spoiler alert.

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Calling obesity a, uh, lifestyle choice is not only

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incorrect, it is also fat shaming.

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So let's put that nonsense to

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rest.

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I am your Chief Medical Explanationist, Dr. Terry

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Simpson, and this is Forku

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Fork University, where we bust myths, make

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sense of the madness, and learn a little bit about food

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and medicine.

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Let's start with the oldest, most tired

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advice in the world. Just eat less

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and move more. It's the go to slogan of

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diet culture, printed on motivational posters

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and yelled by personal trainers everywhere.

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And guess what? It's as useful as

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telling a person with depression to just cheer

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up. If that advice worked, this

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podcast would be about something way more fun,

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like how to make a perfect sourdough bread.

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The reality is, obesity isn't just about

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calories in and calories out. It's a

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complex interplay of your brain, your

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biology, and the world around you. A

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world stuffed to the gills with ultra

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processed foods engineered to make you eat

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more. I'm talking about foods so refined

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they could pass as a contestant on the

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Bachelor. But why do we keep eating them? This

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brings me to my next point. Your brain is not

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your BFF when it comes to food.

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And here's the thing. Your brain has one job when it

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comes to food. To keep you alive. And

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it's stuck in the caveman mode,

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constantly afraid you're going to starve.

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So when you eat that bag of chips or that tub of ice cream,

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your brain throws a party. Why? Because

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these foods are packed with calories. And your brain

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sees calories as survival. The

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problem. Ultra processed foods

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hack to the system. They're designed to hit

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reward centers of your brain harder than a toddler hits a

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pinata. They combine sugar, fat, and

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salt into an unholy trinity of

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deliciousness that keeps you coming back for more.

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Your brain doesn't stand a chance. It's like playing

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poker against a deck full of aces. And you're going to lose

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every time. Oh, and let's not

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forget the lovely hormone Ghrelin. The

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I'm hungry hormone. Think of Ghrelin as

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your annoying co worker who keeps reminding

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you it's lunchtime even though you just ate. And guess

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what? Ultra processed foods can

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Amplify ghrelin's effects, making you

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feel hungrier and eat more. It's a

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vicious cycle.

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Now let's talk about the hero of our story, modern

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medicine and the GLP1s.

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GLP1 is a hormone that helps you regulate your

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appetite. And it's key to understanding why

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obesity isn't just a willpower issue. You

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see, GLP1 tells your brain, hey, you're full. You can stop

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eating now. But for people with

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obesity, that system is out of whack.

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Enter GLP1. Like semaglutide

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or Mounjaro. These medications mimic

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the effect of GLP1, essentially whispering to the brain,

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hey, chill out. You don't need another slice of pizza. And the

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results? People lose a significant amount

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of weight not just because they suddenly develop

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superhuman willpower, but because their biology

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is finally working with them instead of

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against them. And here's the kicker.

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These drugs have shown us that obesity isn't about

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eating too much. It's a disease. A

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complex chronic condition influenced by your

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genes, your hormones, and, yes, that sneaky brain

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of yours. And when you treat it like a

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disease, guess what happens? People get

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better.

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Now, uh, let's tackle the elephant in the room. The idea that

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obesity is a lifestyle choice. I'm just going to say it.

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This is one of the most damaging myths out there. Calling

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obesity a lifestyle choice is like calling an

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asthmatic a bad breathing decision.

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It's not just wrong, it's harmful.

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When we frame obesity as a lifestyle choice, we're

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essentially saying, if you're overweight, it's your fault.

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That kind of thinking leads to the stigmata, shame, and

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discrimination. And guess what? Shame is not a good

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motivator for change. If it were, the

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gym would be packed with people who got roasted at

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Thanksgiving dinner. Let's be clear. When

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lifestyle factors like diet and exercise contribute to

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obesity, they're not the sole cause. Genetics plays a

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massive role, as does the food environment we live

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in. Blaming someone for their obesity is like blaming

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someone for living in a city with terrible air quality. Sure,

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they can try and breathe better, but the odds are stacked against

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them. And let's take a moment to appreciate how

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diabolical ultra processed foods really

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are. These aren't just foods.

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They're science experiments designed to keep you

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eating. They're hyper palatable, calorie

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dense, often stripped of fiber and nutrients.

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It's like the evil twin of a home cooked

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meal. Here's a fun fact. Studies have shown

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that people eat more when they consume ultra

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processed foods. About 500

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calories a day more. And guess what?

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Those calories add up over time. That's

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how you end up with weight gain, metabolic issues, and

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a lifelong addiction to Doritos.

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In my case, maybe it's Reese's. Ultra

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processed foods aren't just bad for your waistline,

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they're bad for your brain. They can hijack your

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dopamine system, making you crave more and more.

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It's like that one X. You can't quit texting at

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2am you know it's bad for you, but you do it

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anyway. So what have we learned today? To

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recap, obesity is a disease. It has

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been diagnosed as a disease since 2013.

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It is not a lifestyle choice. Blaming people

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for their obesity is not only wrong, it's unhelpful

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and cruel. Two, your brain and hormones

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are driving the bus and ultra processed foods are out there slashing

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the tires. Three GLP1 drugs,

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uh, are game changers. They've shown us that treating obesity

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as a medical condition can lead to real society, sustainable

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results. The bottom line, we

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need to stop shaming people for their weight and start

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addressing the root causes of obesity, starting with the food environment

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and the biologic factors that drive

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overconsumption. And here's one final

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kicker. You know your body makes its own

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GLP1. Did you know that ultra

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processed food starts

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feeding bacteria in your

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microbiome that actually destroy the

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cells that make GLP1? So imagine

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this. Ultra processed foods not

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only hack your brain into wanting to eat more, I

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mean, you can't just eat one, but

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they also promote a microbiome or the bacteria in your

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gut that destroy the cells that make your own

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endogenous GLP1. Oh, by the

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way, is there something you can do to help

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your cells make more GLP1 and

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support a healthy microbiome? Yeah, turns out

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eating more fiber, specifically a kind of fiber called

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inulin, can do that. Well, that's

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all for today's episode of Fork youk. If you've learned one thing, let it

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be obesity isn't about bad choices. It's about bad

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systems. And now we understand it better,

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we can start treating it better.

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Until next time, I'm Dr. Terry Simpson, your chief medical

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explanationist, reminding you to love your food, love your body,

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and remember, it's not about the fork in your

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hand. It's about what's at the end of it. This

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episode was written and researched by me, Dr. Terry Simpson.

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You can find references in my blog

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post@yourdoctorsorders.com and

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forku.com and please. If you're going to

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start a diet, start a diet for your nutrition.

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Think about the Mediterranean or the- diet. And on my website,

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Dr.terrysimpson.com, i actually have a course about the Mediterranean

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diet. Before you start any diet,

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please see your doctor. I am not your

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doctor, but someone is. And please make sure

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they're a western trained board certified physician,

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not a chiropractor. Or please see a registered

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dietitian. Your doctor and the dietitian will know

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your particular health issues and can help with

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diet that is good and nutritious and delicious for

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you. Until next time. We'll

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see you later. Have a great week and thanks to our friends at Simpler

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Media and The pod God, Mr. Mr. Evo

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Terra, for helping to distribute this

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episode.

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Remember when you were on the beer and sausage diet?

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Could you just drink one beer?

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You mean one right after another? Uh,

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yeah, sure.

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About the Podcast

Fork U with Dr. Terry Simpson
Learn more about what you put in your mouth.
Fork U(niversity)
Not everything you put in your mouth is good for you.

There’s a lot of medical information thrown around out there. How are you to know what information you can trust, and what’s just plain old quackery? You can’t rely on your own “google fu”. You can’t count on quality medical advice from Facebook. You need a doctor in your corner.

On each episode of Your Doctor’s Orders, Dr. Terry Simpson will cut through the clutter and noise that always seems to follow the latest medical news. He has the unique perspective of a surgeon who has spent years doing molecular virology research and as a skeptic with academic credentials. He’ll help you develop the critical thinking skills so you can recognize evidence-based medicine, busting myths along the way.

The most common medical myths are often disguised as seemingly harmless “food as medicine”. By offering their own brand of medicine via foods, These hucksters are trying to practice medicine without a license. And though they’ll claim “nutrition is not taught in medical schools”, it turns out that’s a myth too. In fact, there’s an entire medical subspecialty called Culinary Medicine, and Dr. Simpson is certified as a Culinary Medicine Specialist.

Where today's nutritional advice is the realm of hucksters, Dr. Simpson is taking it back to the realm of science.

About your host

Profile picture for Terry Simpson

Terry Simpson

Dr. Terry Simpson received his undergraduate, graduate, and medical degrees from the University of Chicago where he spent several years in the Kovler Viral Oncology laboratories doing genetic engineering. Until he found he liked people more than petri dishes. Dr. Simpson, a weight loss surgeon is an advocate of culinary medicine, he believes teaching people to improve their health through their food and in their kitchen. On the other side of the world, he has been a leading advocate of changing health care to make it more "relationship based," and his efforts awarded his team the Malcolm Baldrige award for healthcare in 2018 and 2011 for the NUKA system of care in Alaska and in 2013 Dr Simpson won the National Indian Health Board Area Impact Award. A frequent contributor to media outlets discussing health related topics and advances in medicine, he is also a proud dad, husband, author, cook, and surgeon “in that order.”