Episode 110

Ultra-Processed Food The Enemy

Published on: 8th January, 2026

Ultra-Processed Food: Making Sense of the Madness

Ultra-processed food has become the villain of modern nutrition.

Scroll through social media, and you’ll hear that it’s poisoning us, wrecking our gut, and driving the obesity epidemic all by itself.

At the same time, other voices dismiss the entire idea as fear-mongering.

According to them, processing doesn’t matter at all.

Neither extreme tells the full story.

So instead of slogans, let’s talk about what ultra-processed food actually means, why people want to blame it, where the science is strong, and where it starts to drift into storytelling.


Why We’re Looking for Something to Blame

The obesity epidemic is real.

Rates have climbed for decades, and people understandably want answers.

Human biology didn’t suddenly change in the 1980s.

Willpower didn’t vanish overnight.

Something in our environment shifted.

Food is an obvious suspect.

Because food changed, many people assume there must be a single culprit hiding in the ingredient list.

That belief leads to bold claims.

Some say Europe bans certain additives and therefore avoids obesity.

In reality, obesity rates continue to rise across Europe as well.

Others argue that specific ingredients damage the gut, letting in more calories or triggering metabolic chaos.

Those ideas sound scientific, especially when they involve complex biology.

However, when a problem is large and complicated, humans naturally want a cause that feels simple and controllable.

Blaming one ingredient feels easier than confronting patterns of eating, stress, time pressure, and convenience.

Biology, unfortunately, rarely offers cinematic villains.


What “Ultra-Processed” Actually Means

To understand the debate, definitions matter.

Researchers use the NOVA classification system to describe food processing.

NOVA does not rate healthfulness.

Instead, it categorizes food by how manufacturers produce it.

The system includes four groups.

First come whole or minimally processed foods, such as vegetables, beans, eggs, and fish.

Next are culinary ingredients like oil, sugar, salt, and flour.

Then come processed foods, including bread, cheese, yogurt, and canned vegetables.

Finally, NOVA defines ultra-processed foods as industrial formulations.

These products often combine refined ingredients with additives, stabilizers, emulsifiers, and flavor systems that home cooks rarely use.

Here’s the crucial point.

Ultra-processed food is defined by how it is made, not by what it does in the body.

That distinction often gets lost.

As a result, soda and whole-grain bread can fall into the same category, even though they behave very differently nutritionally.


Why Ingredient Blame Falls Short

At this point, many discussions take a wrong turn.

Instead of asking how people eat, the conversation focuses on what to ban.

Ingredients become the enemy.

Yet most claims about additives rely on animal studies using doses far higher than what humans consume.

Human data remains limited and inconsistent.

Meanwhile, the bigger picture often gets ignored.

Ultra-processed food correlates with stress, long work hours, poor sleep, and limited time for cooking.

Those factors influence eating behavior regardless of ingredients.

When people feel rushed and overwhelmed, they don’t just eat differently.

They eat faster, snack more often, and rely on foods that require little effort.

That context matters.


The Simple Question That Changed the Conversation

Instead of chasing villains, one researcher asked a much simpler question.

Do people eat more when food is ultra-processed, even when nutrition looks the same on paper?

That question led to the most important experiment in this entire debate.


What Kevin Hall Actually Found

At the National Institutes of Health, Kevin Hall conducted a tightly controlled feeding study.

Participants lived in a metabolic ward.

Researchers controlled the environment, the meals, and the measurements.

Each participant ate two diets.

One diet consisted mostly of ultra-processed foods.

The other relied on minimally processed foods.

Importantly, researchers matched calories, protein, fat, carbohydrates, sugar, and salt.

People could eat as much as they wanted.

The result surprised almost everyone.

On the ultra-processed diet, participants consumed about 500 extra calories per day.

Yet, they didn’t report more hunger.

They didn’t feel less full.

However, they simply ate more.

This finding matters because it avoids speculation.

No ingredient theories appear here.

No gut damage claims drive the conclusion.

Ultra-processed food made it easier to eat more calories without noticing.

Sometimes the most powerful answers are also the least dramatic.


Why a Book Made This Go Viral

That study helped fuel widespread interest, including the success of Ultra-Processed People: The Science Behind Food That Isn't Food by Chris van Tulleken.

Van Tulleken, a British physician, took a personal approach.

He ate a diet dominated by ultra-processed foods and documented the effects.

Weight gain followed.

Hunger became harder to regulate.

Energy and mood shifted.

The book resonated because it made an abstract concept feel personal.

It also highlighted how modern foods often prioritize shelf life, softness, and convenience.

Stories like this help people recognize patterns they already sense in daily life.

However, a compelling narrative does not replace careful interpretation.


Where the Story Goes Too Far

Ultra-processed food is not one thing.

It does not act through a single mechanism.

The research faces several challenges.

First, heterogeneity clouds interpretation.

Grouping soda and yogurt together creates confusion rather than clarity.

Second, confounding remains a major issue.

People who eat more ultra-processed food often face structural barriers that affect health in many ways.

Third, additive panic oversimplifies biology.

Mouse data cannot stand in for long-term human outcomes.

Ultra-processed food may contribute to health problems, but it rarely acts alone.


A Better Way to Think About Food

Rigid rules tend to fail.

Real eating happens in real life.

Instead of asking whether a food qualifies as ultra-processed, better questions help guide choices.

Does the food contain fiber?

How will it contribute protein or micronutrients?

Finally, will it replace a balanced meal or help create one?

Can you eat it mindfully and stop when satisfied?

Foods like yogurt, tofu, olive oil, canned beans, and frozen vegetables often break simplistic rules.

Yet they support healthy eating patterns when used well.

Processing did not ruin our food.

Confusion did.


The Bottom Line

People want a villain because villains feel actionable.

Science, however, often points toward behavior rather than ingredients.

Ultra-processed foods encourage faster eating, softer textures, and higher calorie intake.

That pattern explains a great deal without invoking conspiracies.

Understanding that reality empowers better choices than fear ever could.


Reference

Hall KD, Ayuketah A, Brychta R, et al. Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial. Cell Metabolism. 2019;30(1):67–77.e3.

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About the Podcast

Fork U with Dr. Terry Simpson
Learn more about what you put in your mouth.
Fork U(niversity)
Not everything you put in your mouth is good for you.

There’s a lot of medical information thrown around out there. How are you to know what information you can trust, and what’s just plain old quackery? You can’t rely on your own “google fu”. You can’t count on quality medical advice from Facebook. You need a doctor in your corner.

On each episode of Your Doctor’s Orders, Dr. Terry Simpson will cut through the clutter and noise that always seems to follow the latest medical news. He has the unique perspective of a surgeon who has spent years doing molecular virology research and as a skeptic with academic credentials. He’ll help you develop the critical thinking skills so you can recognize evidence-based medicine, busting myths along the way.

The most common medical myths are often disguised as seemingly harmless “food as medicine”. By offering their own brand of medicine via foods, These hucksters are trying to practice medicine without a license. And though they’ll claim “nutrition is not taught in medical schools”, it turns out that’s a myth too. In fact, there’s an entire medical subspecialty called Culinary Medicine, and Dr. Simpson is certified as a Culinary Medicine Specialist.

Where today's nutritional advice is the realm of hucksters, Dr. Simpson is taking it back to the realm of science.

About your host

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Terry Simpson

Dr. Terry Simpson received his undergraduate, graduate, and medical degrees from the University of Chicago where he spent several years in the Kovler Viral Oncology laboratories doing genetic engineering. Until he found he liked people more than petri dishes. Dr. Simpson, a weight loss surgeon is an advocate of culinary medicine, he believes teaching people to improve their health through their food and in their kitchen. On the other side of the world, he has been a leading advocate of changing health care to make it more "relationship based," and his efforts awarded his team the Malcolm Baldrige award for healthcare in 2018 and 2011 for the NUKA system of care in Alaska and in 2013 Dr Simpson won the National Indian Health Board Area Impact Award. A frequent contributor to media outlets discussing health related topics and advances in medicine, he is also a proud dad, husband, author, cook, and surgeon “in that order.”